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Sources: Pro Clinic with Dr. Thomas Cunningham MD on Supplementation and Biohacking

Whey Protein

Zhao S, Xu Y, Li J, Ning Z. The Effect of Plant-Based Protein Ingestion on Athletic Ability in Healthy People- A Bayesian Meta-Analysis with Systematic Review of Randomized Controlled Trials. Nutrients. 2024 Aug 17;16(16):2748. doi: 10.3390/nu16162748. PMID: 39203884; PMCID: PMC11357476.

 

Creatine

Sandkühler, J.F., Kersting, X., Faust, A. et al. The effects of creatine supplementation on cognitive performance—a randomised controlled study. BMC Med 21, 440 (2023). https://doi.org/10.1186/s12916-023-03146-5

 

Beta Alanine

Sas-Nowosielski K, Wyciślik J, Kaczka P. Beta-Alanine Supplementation and Sport Climbing Performance. Int J Environ Res Public Health. 2021 May 18;18(10):5370. doi: 10.3390/ijerph18105370. PMID: 34069981; PMCID: PMC8157844.

 

 

Collagen

García-Coronado, J.M., Martínez-Olvera, L., Elizondo-Omaña, R.E. et al. Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials. International Orthopaedics (SICOT) 43, 531–538 (2019). https://doi.org/10.1007/s00264-018-4211-5

Khatri, M., Naughton, R.J., Clifford, T. et al. The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino Acids 53, 1493–1506 (2021). https://doi.org/10.1007/s00726-021-03072-x

Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K. Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis. Am J Clin Nutr. 2017 Jan;105(1):136-143. doi: 10.3945/ajcn.116.138594. Epub 2016 Nov 16. PMID: 27852613; PMCID: PMC5183725.

Jacinto JL, Nunes JP, Gorissen SHM, Capel DMG, Bernardes AG, Ribeiro AS, Cyrino ES, Phillips SM, Aguiar AF. Whey Protein Supplementation Is Superior to Leucine-Matched Collagen Peptides to Increase Muscle Thickness During a 10-Week Resistance Training Program in Untrained Young Adults. Int J Sport Nutr Exerc Metab. 2022 May 1;32(3):133-143. doi: 10.1123/ijsnem.2021-0265. Epub 2022 Jan 17. PMID: 35042187. (not strength superior)

Bischof K, Moitzi AM, Stafilidis S, König D. Impact of Collagen Peptide Supplementation in Combination with Long-Term Physical Training on Strength, Musculotendinous Remodeling, Functional Recovery, and Body Composition in Healthy Adults: A Systematic Review with Meta-analysis. Sports Med. 2024 Jul 26. doi: 10.1007/s40279-024-02079-0. Epub ahead of print. PMID: 39060741.

 

Citruline mallate

Burgos J, Viribay A, Fernández-Lázaro D, Calleja-González J, González-Santos J, Mielgo-Ayuso J. Combined Effects of Citrulline Plus Nitrate-Rich Beetroot Extract Co-Supplementation on Maximal and Endurance-Strength and Aerobic Power in Trained Male Triathletes: A Randomized Double-Blind, Placebo-Controlled Trial. Nutrients. 2021 Dec 23;14(1):40. doi: 10.3390/nu14010040. PMID: 35010917; PMCID: PMC8746866.